エベロリムスは患者から導出された多能性幹細胞由来の循環器系平滑筋細胞におけるエラスチン不全表現型を回復する



Everolimus Rescues the Phenotype of Elastin Insufficiency in Patient Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells.

Kinnear C(1)(2), Agrawal R(1), Loo C(3), Pahnke A(4)(5), Rodrigues DC(2), Thompson T(2), Akinrinade O(1), Ahadian S(4)(5), Keeley F(6)(7), Radisic M(4)(5), Mital S(1)(8), Ellis J(2)(3).
Author information:
(1)From the Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada (C.K., R.A., O.A., S.M.).
(2)Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada (C.L., D.C.R., T.T., J.E.).
(3)Department of Molecular Genetics, University of Toronto, Ontario, Canada (C.L., J.E.).
(4)Institute of Biomaterials and Biomedical Engineering, University of Toronto, Ontario, Canada (A.P., S.A., M.R.).
(5)Department of Chemical Engineering and Applied Chemistry, University of Toronto, Ontario, Canada (A.P., S.A., M.R.).
(6)Department of Biochemistry, University of Toronto, Ontario, Canada (F.K.).
(7)Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada (F.K.).
(8)Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada (S.M.).
Arterioscler Thromb Vasc Biol. 2020 Mar 26:ATVBAHA119313936. doi: 10.1161/ATVBAHA.119.313936. [Epub ahead of print]

【目的】 【方法と結果】 【結論】 【訳者注】 (2020年3月)



目次に戻る